Abstract: Five olefins were aminohydroxylated enantiomerically catalyzed by 1,4-bis(9-O-quininyl)phthalazine-OsO₄ complex in the presence of benzyl N-chlorocarbamate(oxidant and nitrogen source). Excellent enantioselectivity(85%—99% e.e.) as well as specific regio and chemoselectivity were observed and isolated yield of the products 48%—68% was achieved. The results are comparable to those of the best catalyst reported for AA reaction.

Key words: Bis(9-O-quininyl)phthalazine, Asymmetric aminohydroxylation, Chiral β-amino alcohol