Abstract:

Currently, porous inorganic xerogels are particularly attractive matrices for electrochemical biosensors since they combine physical rigidity, negligible swelling in aqueous solutions, chemical inertness, and high photochemical, biodegradational, and thermal stability. The process parameters can be selected to provide an effective matrix to entrap the enzymes, which can retain their functional characteristics and activity to a large extent. The porosity in the sol-gel matrix plays an important role for the selective and effective interaction between the entrapped enzyme and substrate in the sample milieu.