CJCU

Chem. J. Chinese Universities ›› 1994, Vol. 15 ›› Issue (6): 859.

• Articles • Previous Articles     Next Articles

Rubicunoside A─a New Acetylated Triterpenoid Saponin from Silene Rubicunda

TAN Ning-Hua1, ZHOU Shou-Xun1, ZHOU Jun2, CHENG Chang-Xiang2, WANG De-Zu2, HE Yi-Neng2   

  1. 1. Department of Phytochemistry, China Pharmaceutical University, Nanjing;
    2. Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, 650204
  • Received:1993-11-27 Revised:1994-04-07 Online:1994-06-24 Published:1994-06-24

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Abstract: Anew acetylated triterpenoid saponin, rubicunoside A(1), was isolated from the roots of Silene rubicunda.On the basis of extensive chemical, enzymic, and spectral methods the structure was elucidated as 3-O-β-D-galactopyranosyl-(1-2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucuronopyranosyl quillaic acid 28-O-β-D-xylopyranosyl-(1-3)-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→3)-[2'-OAc]-β-D-fucopyranosyl-(1-2)-[3'-OAc]-β-D-fucopyranoside(1).The enzymic cleavage method with glyrrhizinic acid hydrolase providing selectively 3-oligosaccharides and 28-O-glucosides, and partial methanolysis providing selectively 28-oligosaccharides from 3, 28-O-bisglucosides were effective for the structure elucidation.

Key words: Silene rubicunda, Caryophyllaceae, Triterpenoid saponin, Rubicunoside A, Glyrrhizinic acid hydrolase

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