Abstract: The desorption kinetics of H₂ from the Cu/ZnO/Al₂O₃ catalyst of the low temperature shift reaction has been studied by TPD.It is represented that, for H₂, Cu/ZnO/Al₂O₃ has two active sites (Ⅰ) and (Ⅱ) which have distinct characteristics of energy as the temperature <350℃.The detailed analysis for (Ⅰ) and (Ⅱ) with the desorption rate isotherms method gave the desortion kinetic parameters and determined the desorption rate equations.It was discovered that the effective surface of Cu/ZnO/Al₂O₃ catalyst is not an ideal surface and the contribution for effective surface area is 27.6% for (Ⅰ) and 72.4% for (Ⅱ).