Abstract: O-Benzoyl-,O-( 3,4,5-trimethoxybenzoyl)-, O-( 4-chloro-benzoyl)-and O-(4-nitrobenzoyl)- pyridine-2- and 4-aldoximes were synthesized conveniently from the acylation of pridine-2-and 4-aldoximes with corresponding aroyl chlorides by a modified procedure. From the quaterniza-tion of O-benzoyl, O-(3, 4, 5-trimethoxy-benzoyl)-and O-(4-chlorobenzoyl) -piridine-4-aldoximes with methyl iodide the normal methiodides were obtained, but during the quaternization of the corresponding derivatives of 2-aldoximes the β-elimination also occurred so that only the abnormal product of 2-cyanopiridine methiodide was formed. Both O-( 4-nitroben-zoyl )-piridine-2- and 4-aldoximes reacted not with methyl iodide.