Chem. J. Chinese Universities ›› 2009, Vol. 30 ›› Issue (12): 2491.

• Articles • Previous Articles     Next Articles

Adhesion and Proliferation of Osteoblast on the Amidation Surface of Polylactide Film

TIAN Ye1,2, WANG Ying-Jun1,2, ZHOU Chang-Ren3*, ZENG Qing-Hui3, TAN Guo-Xing4   

  1. 1. Key Laboratory of Special Functional Materials, Ministry of Education,
    2. School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China;
    3. Department of Materials Science and Engineering, Jinan University, Guangzhou 510632, China;
    4. Institute of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, China
  • Received:2009-03-27 Online:2009-12-10 Published:2009-12-10
  • Contact: ZHOU Chang-Ren. E-mail: tcrz9@jnu.edu.cn
  • Supported by:

    国家自然科学基金(批准号: 50732003, 50830101, 50803018)和广东省自然科学基金(批准号: 4205786)资助.

Abstract:

Acrylic amide(AAm) was polymerized onto polylactide(PLA) film via UV irradiation to achieve amidation surface, furthermore the adhesion and proliferation of osteoblast on this surface was investigated. The results show that the hydrophilicity of PLA film is improved by introduction amido: the contact angle decreases from 78° to 56° and the free energy increases from 42.7 mJ/m2 to 51.4 mJ/m2. Compared with the control, osteoblast spread out more filopodia after 3 d incubation on amidation surface, and it entered cell division phase more quickly, which indicated that the surface amidation could promote the cell′s adhesion and proliferation on the PLA film.

Key words: Polylactide; Amidation surface; Graft polymerization; Adhesion and proliferation

TrendMD: