Synthesis, Characterization and Biological Functionalization of Superparamagnetic/Fluorescent Bifunctional Nanoparticles

Chem. J. Chinese Universities

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Synthesis, Characterization and Biological Functionalization of Superparamagnetic/Fluorescent Bifunctional Nanoparticles

TAN Fang¹, ZHUANG Zhi-Xia^1,2*, YANG Huang-Hao², CHEN Cheng-Xiang¹, WANG Xiao-Ru^1,2

1. The Key Laboratory of Analytical Sciences of MOE, Department of Chemistry, Xiamen University, Xiamen 361005, China;
2. The First Institute of Oceanography, SOA, Qingdao 266061, China

Received:2006-12-01 Revised:1900-01-01 Online:2007-08-10 Published:2007-08-10
Contact: ZHUANG Zhi-Xia

Abstract

Abstract: A novel class of fluorescent/superparamagnetic bifunctional nanoparticles was synthesized via the reverse microemulsion technique. These nanoparticles were studied with transmission electron microscopy(TEM) and SQUID microscopy. The results show that these nanoparticles have a typical diameter of 40 nm and a saturated magnetic moment of 1.9 emu/g at room temperature. The experiment results also show that these nanoparticles exhibit a strong excitonic photoluminescence. Then, these bifunctional nanoparticles were modified with vancomycin for binding. The results show that these vancomycin modified nanoparticles can capture selectively bacterias.

Key words: Superparamagnetics, Fluorescence, Nanoparticle, Biological functionalization

CLC Number:

O657.2
O647

TrendMD:

TAN Fang¹, ZHUANG Zhi-Xia^1,2*, YANG Huang-Hao², CHEN Cheng-Xiang¹, WANG Xiao-Ru^1,2. Synthesis, Characterization and Biological Functionalization of Superparamagnetic/Fluorescent Bifunctional Nanoparticles[J]. Chem. J. Chinese Universities, doi: .

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Synthesis, Characterization and Biological Functionalization of Superparamagnetic/Fluorescent Bifunctional Nanoparticles

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