Synthesis and Biological Activity of Silicon-containing Phosphorodithioates

Abstract

Abstract: Silylmethanethiols R¹R²MeSiCH₂SHsmoothly undergo Mannich-type condensation reaction with O,O-dialkyl phosphorodithioates (RO)₂P(S)SHand formaldehyde.By utilizing the above reaction and nucleophilic substitution of O,O-diethyl-S-(2-bromoethyl)phos phorodithioate with silylmethanethiols, 37 novel si1icon-containing phosphorodithioates (RO)₂P (S)S (CH₂)_nSCH₂SiMe R¹R² (n = 1, 2) were synthesized.The bioassay results show that the main title compounds possess some insecticidal and acaricidal activities at the preliminary screening concentration.

Key words: Organosilicon compound, Phosphorodithioate, Synthesis, Biological activity

TrendMD:

HE Zheng-Jie, LI Zheng-Ming, BI Fu-Chun, WANG Wen-Li. Synthesis and Biological Activity of Silicon-containing Phosphorodithioates[J]. Chem. J. Chinese Universities, 1997, 18(5): 739.

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Synthesis and Biological Activity of Silicon-containing Phosphorodithioates

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