乏氧激活化疗药物AQ4N与碳点自组装用于化疗联合声动力治疗肿瘤

庞娥, 唐垣钰, 赵少静, 程强, 王晨, 陈健敏, 蓝敏焕

Hypoxia Activated Chemotherapy Drug AQ4N and Carbon Dots Self-assembly for Chemotherapy Combined with Sonodynamic Therapy of Tumors

PANG E, TANG Yuanyu, ZHAO Shaojing, CHENG Qiang, WANG Chen, CHEN Jianmin, LAN Minhuan

Fig.3 In vitro cellular experiments in different treatment groups Fluorescence images of 4T1 cells were stained using DCFH-DA probe（A） or Calcein AM/PI（B） after different treatments； the viability of 4T1 cells was incubated using different concentrations of CDs@AQ4N in normoxic（C） and hypoxic condition（D） with or without US irradiation（1.0 W/cm2， 100% duty cycle， 30 s）.