%0 Journal Article %A Zongxuan TONG %A Qinqin HU %A Hongzhou GU %T Deoxyribozymes: Selection, Biosensing and Outlook %D 2020 %R 10.7503/cjcu20200397 %J Chemical Journal of Chinese Universities %P 2345-2355 %V 41 %N 11 %X

In this review, we briefly describe the origin of deoxyribozymes and the selection strategies for the isolation of these deoxyribonucleic acid(DNA) enzymes. We compare deoxyribozymes with ribozymes and protein enzymes. We focus on the recently developed product-capturing and cancelling selection strategies, as well as the metal-ion-specific and particular-biological-sample-sensing ribonucleic acid(RNA)-cleaving deoxyribozymes which have worked as molecular tools in many aspects. In the end, we summarize the challenges for the deoxyribozyme field that need to be tackled down in the future.

%U http://www.cjcu.jlu.edu.cn/EN/10.7503/cjcu20200397